The heart pumps blood to the human body. Artificial hearts are implanted in patients suffering from severe heart diseases. For the artificial heart system, we need to consider body fluids such as: Blood, intracellular fluids, extra cellular fluids, intravenous fluids and artificial (synthetic) blood. The use of anticoagulants (Heparin or Coumarin) is necessary in the implantation of an artificial organ. These act as blood thinners and prevent thromboembolism. Cardiovascular biomaterials are used to develop artificial heart valves, mechanical heart valves, pacemakers, vascular grafts, oxygenerators and cardiac assist systems (medical devices) like total artificial hearts, intra-aortic balloon pumps etc. Some of the biomaterials used in medicine are metals, polymers ceramics and hydrogels.